PHARMADEV Pharmacochimie et Biologie pour le Développement

Publications PEPS




  • Trinel M, Jullian V, Le Lamer AC, Mhamdi I, Mejia K, Castillo D, Cabanillas BJ, Fabre N. Profiling of Hura crepitans L. latex by ultra-high-performance liquid chromatography/atmospheric pressure chemical ionisation linear ion trap Orbitrap mass spectrometry. Phytochemical Analysis 2018, 29, 627-638.
  • Villaret J, Marti G, Dubois F, Reybier K, Gaudre N, Haddad M*, Valentin A*. Adaptation of a microbead assay for the easy evaluation of traditional anti-sickling medicines: application to DREPANOSTAT and FACA. Pharmaceutical Biology 56, 385-392.
  • Chassagne F, Haddad M, Amiel A, Phakeovilay C, Manithip C, Bourdy G, Deharo E, Marti G. A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. Fitoterapia 127, 226-236.
  • Mejai A, Najahi E, Tchani G, Perio P, Vendier L, Bourgeade Delmas S, Abidi R, Haddad M, Nepveu F* and Reybier K*. Synthesis and Evaluation of Antiplasmodial Activities of Fluorinated 6-Amino- 2-Aryl-3H-Indolone-N-Oxides. Med Chem 2018, 8:4.
  • Haidara M, Haddad M, Denou A, Marti G, Bourgeade-Delmas S, Sanogo R, Bourdy G, Aubouy A. In vivo validation of anti-malarial activity of crude extracts of Terminalia macroptera, a Malian medicinal plant. Malaria Journal 17, 68.
  • Auditeau E, Moyano LM, Bourdy G, Nizard M, Jost J, Ratsimbazafy V, Preux PM, Boumediene F. Herbal medicine uses to treat people with epilepsy: A survey in rural communities of northern Peru. Journal of Ethnopharmacology 215, 184-190.
  • Rojas TR, Bourdy G, Ruiz E, Cerapio JP, Pineau P, Gardon J, Doimi F, Deparis X, Deharo E, Bertani S. Herbal Medicine Practices of Patients With Liver Cancer in Peru: A Comprehensive Study Toward Integrative Cancer Management. Integrative Cancer Therapies, 17, 52-64.
  • Lyoussi B., Cherkaoui T. K., Cherkaoui T. K., Morel N., Haddad M. and Quetin-Leclercq J. (2018). “Evaluation of cytotoxic effects and acute and chronic toxicity of aqueous extract of the seeds of Calycotome villosa (Poiret) Link (subsp. intermedia) in rodents.” Avicenna J Phytomed 2018, 8, 122-135.
  • Gadea A, Le Lamer AC., Le Gall S, Jonard, C, Ferron, S, Catherine, D, Ertz, D, Le Pogam, P, Boustie J, Le Dévéhat F, Charrier, M. Intrathalline metabolite profiles in the lichen Argopsis friesiana shape gastropod grazing patterns. Journal of Chemical Ecology 2018, 44, 471-482.
  • Guzmán J., Téné N., Touchard A., Castillo D., Belkhelfa H., Haddioui-Hbabi L., M. Treilhou M., Sauvain M. (2018) Anti-Helicobacter pylori properties of the ant-venom peptide bicarinalin. Toxins, 10: 21-30.





  • Alvarez D., Wilkinson K. A., Treilhou M., Tene N., Castillo D., Sauvain M. (2017). Characterization of anti-Helicobacter pylori peptides present in the hemolymph of Hermetia illucens larvae. American Journal of Tropical Medicine and Hygiene, 97 (5), 357-357.
  • Azando E. V. B., Olounlade A. P., Hounzangbe-Adote M. S., Ha T. B. T., Fabre N., Valentin A. (2017). Control of gastro-intestinal parasites with essential oil from Zanthoxylum zanthoxyloides (Fagara zanthoxyloides). Revue De Medecine Veterinaire, 168 (10-12), 205-212.
  • Bourdy G, Aubertin C, Jullian V, Deharo E. (2017). Quassia “”biopiracy”” case and the Nagoya Protocol : a researcher’s perspective. Journal of Ethnopharmacology, 206, 290-297.”
  • Gadea A, Le Pogam P, Biver G, Boustie J, Le Lamer AC, Le Dévéhat F, Charrier M. Which Specialized Metabolites Does the Native Subantarctic Gastropod Notodiscus hookeri Extract from the Consumption of the Lichens Usnea taylorii and Pseudocyphellaria crocata? Molecules. 2017 Mar 8;22(3)
  • Guzman J., Téné N., Touchard A., Castillo D., Belkhelfa H., Haddioui-Hbabi L., Treilhou M., Sauvain M. 2017. Anti-Helicobacter pylori Properties of the Ant-Venom Peptide Bicarinalin. Toxins 29, 10.
  • Hoang Nam Pham, Michalet S., Bodillis J., Tien Dat Nguyen, Thi Kieu Oanh Nguyen, Thi Phuong Quynh Le, Haddad M, Nazaret S., Dijoux-Franca M. G. (2017). Impact of metal stress on the production of secondary metabolites in Pteris vittata L. and associated rhizosphere bacterial communities. Environmental Science and Pollution Research, 24 (20), 16735-16750.
  • Nasri I., Chawech R., Girardi C., Mas E., Ferrand A., Vergnolle N., Fabre N, Mezghani-Jarraya R., Racaud-Sultan C. (2017). Anti-inflammatory and anticancer effects of flavonol glycosides from Diplotaxis harra through GSK3 beta regulation in intestinal cells. Pharmaceutical Biology, 55 (1), 124-131.
  • Odonne G., Houël E., Bourdy G, Stien D. (2017). Treating leishmaniasis in Amazonia: a review of ethnomedicinal concepts and pharmaco-chemical analysis of traditional treatments to inspire modern phytotherapies. Journal of Ethnopharmacology, 199, 211-230.
  • Vasquez-Ocmin P., Haddad M, Gadea A, Jullian V, Castillo D., Paloque L., Cerapio J. P., Bourdy G, Sauvain M. (2017). A new phthalide derivative from Peperomia nivalis. Natural Product Research, 31 (2), 138-142.
  • Zebiri I., Gratia A., Nuzillard J. M., Haddad M, Cabanillas B., Harakat D., Voutquenne-Nazabadioko L. (2017). New oleanane saponins from the roots of Dendrobangia boliviana identified by LC-SPE-NMR. Magnetic Resonance in Chemistry, 55 (11), 1036-1044.
  • Zebiri I., Haddad M, Duca L., Sauvain M, Paloque L., Cabanillas B., Rengifo E., Behr J. B., Voutquenne-Nazabadioko L.  (2017). Biological activities of triterpenoids from Poraqueiba sericea stems. Natural Product Research, 31 (11), 1333-1338.





  • Cabanillas B., Vasquez-Ocmin P., Zebiri I., Rengifo E., Sauvain M, Le H. L., Vaisberg A., Voutquenne-Nazabadioko L., Haddad M. (2016). A new 5-alkylresorcinol glucoside derivative from Cybianthus magnus. Natural Product Research, 30 (3), 293-298.
  • Chassagne F, Bourdy G, Deharo E, Sovanmoly H : Natural remedies used by Bunong people in Mondulkiri province, Northeast Cambodia. (2016). J Ethnopharmacol Sep;191:41-70.
  • Chassagne F., Hul S., Deharo E, Bourdy G. (2016). Natural remedies used by Bunong people in Mondulkiri province (Northeast Cambodia) with special reference to the treatment of 11 most common ailments. Journal of Ethnopharmacology, 191, 41-70.
  • Chassagne F., Rojas T. R., Bertani S, Bourdy G, Eav S., Ruiz E., Pineau P., Deharo E. (2016). A 13-year retrospective study on primary liver cancer in Cambodia: a strikingly high hepatitis C occurrence among hepatocellular carcinoma cases. Oncology, 91 (2), 106-116.
  • Chervin J., Marti G., Perio P, Martins N., Reybier K., Nepveu F., Fabre N., Vilarem G., Talou T. (2016). LC-MS based metabolomic approach applied to bioactive molecules identification: case study of a comprehesive chemodiversity screening of Viola genus. Planta Medica, 82 (S 01).
  • Girardi C., Jullian V, Haddad M, Vansteelandt M., Cabanillas B. J., Kapanda C. N., Herent M. F., Quetin-Leclercq J., Fabre N. (2016). Analysis and fragmentation mechanisms of hirsutinolide-type sesquiterpene lactones by ultra-high-performance liquid chromatography/electrospray ionization linear ion trap Orbitrap mass spectrometry. Rapid Communications in Mass Spectrometry, 30 (5), 569-580.
  • Haidara M., Bourdy G, De Tommasi N., Braca A., Traore K., Giani S., Sanogo R. (2016). Medicinal plants used in Mali for the treatment of malaria and liver diseases. Natural Product Communications, 11 (3), 339-352.
  • Houel E., Nardella F., Jullian V, Valentin A., Vonthron-Senecheau C., Villa P., Obrecht A., Kaiser M., Bourreau E., Odonne G., Fleury Marie, Bourdy G, Eparvier V., Deharo E, Stien D. (2016). Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians. Journal of Ethnopharmacology, 187, 241-248.
  • Le Pogam P, Le Lamer AC, Legouin B, Boustie J, Rondeau D. (2016). In situ DART-MS as a Versatile and Rapid Dereplication Tool in Lichenology: Chemical Fingerprinting of Ophioparma ventosa. PHYTOCHEMICAL ANALYSIS, 27 (6), 354-363.
  • Le Pogam P, Le Lamer AC, Siva B, Legouin B, Bondon A, Graton J, Jacquemin D, Rouaud I, Ferron S, Obermayer W, Babu KS, Boustie J. (2016). Minor Pyranonaphthoquinones from the Apothecia of the Lichen Ophioparma ventosa. Journal Of Natural Products, 79 (4), 1005-1011.
  • Le Pogam P, Legouin B, Geairon A, Rogniaux H, Lohezic-Le Devehat F, Obermayer W, Boustie J, Le Lamer AC. (2016). Spatial mapping of lichen specialized metabolites using LDI-MSI: chemical ecology issues for Ophioparma ventosa. Scientific Reports, 6, 37807.
  • Mollinedo P., Vila J. L., Arando H., Sauvain M, Deharo E, Bravo J. A. (2016). Anti-infective assessment of Senecio smithioides (Asteraceae) and isolation of 9-oxoeuryopsin, a furanoeremophilane-type sesquiterpene with antiplasmodial activity. Natural Product Research, 30 (22), 2594-2597.
  • Zebiri I., Haddad M, Duca L., Harakat D., Cabanillas B., Paloque L., Scandolera A., Sauvain M, Rengifo E., Voutquenne-Nazabadioko L.  (2016). Zebiriosides A-L, oleanane saponins from the roots of Dendrobangia boliviana. Phytochemistry, 130, 262-272.





  • Carraz M, Lavergne C., Jullian V, Wright M., Gairin J. E., de la Cruz M. G., Bourdy G. (2015). Antiproliferative activity and phenotypic modification induced by selected Peruvian medicinal plants on human hepatocellular carcinoma Hep3B cells. Journal of Ethnopharmacology, 166, 185-199.
  • Girardi C., Fabre N, Paloque L., Ramadani A. P., Benoit-Vical F., Gonzalez-Aspajo G., Haddad M, Rengifo E., Jullian V. (2015). Evaluation of antiplasmodial and antileishmanial activities of herbal medicine Pseudelephantopus spiralis (Less.) Cronquist and isolated hirsutinolide-type sesquiterpenoids. Journal of Ethnopharmacology, 170, 167-174.
  • Gonzalez-Aspajo G., Belkhelfa H., Haddioui-Hbabi L., Bourdy G, Deharo E. 2015. Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro. Journal of Ethnopharmacology, 171, 330-334.
  • Houel E., Fleury Marie, Odonne G., Nardella F., Bourdy G, Vonthron-Senecheau C., Villa P., Obrecht A., Eparvier V., Deharo E, Stien D. (2015). Antiplasmodial and anti-inflammatory effects of an antimalarial remedy from the Wayana Amerindians, French Guiana: takamalaime (Psidium acutangulum Mart. ex DC., Myrtaceae). Journal of Ethnopharmacology, 166, 279-285. ISSN 0378-8741
  • Le H. L., Jullian V, Claparols C., Vansteelandt M., Haddad M, Cabou C., Deharo E, Fabre N. (2015). Development and validation of liquid chromatography combined with tandem mass spectrometry methods for the quantitation of simalikalactone E in extracts of Quassia amara L. and in mouse blood. Phytochemical Analysis, 26 (2), 111-118.
  • Marchand P., Bazin M. A., Pagniez F., Riviere G., Bodero L., Marhadour S., Nourrisson M. R., Picot C., Ruchaud S., Bach S., Baratte B., Sauvain M, Pareja D. C., Vaisberg A. J., Le Pape P. (2015). Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines. European Journal of Medicinal Chemistry, 103, 381-395.
  • Mollinedo P., Vila J.L., Arando ACL Sauvain M., Deharo E, Bravo J.A. 9-Oxoeuryopsin, antimalarial furanoeremophilane-type sesquiterpene from Senecio smithioides (Asteraceae). (2015). Nat. Prod. Res. 25: 1-4.
  • Tubéry P., Ragot, J. Lagarde P., Authier-Derivaux D., Pidoux M., Rasolohery C., Bourdy G. 2015. Desmodium adscendens. From the cameroonian traditional remedy against hepatitis to chemotherapy support. Hegel, 5 (4).
  • Valadeau C. et Bourdy G. 2015. Le corps de l’homme l’esprit des plantes : soigner chez les yaneshas en haute amazonie péruvienne. Editions IRD., 356p





  • Blanchet E, Vansteelandt M, Le Bot R, Egorov M, Guitton Y, Pouchus YF, Grovel O. (2014). Synthesis and antiproliferative activity of ligerin and new fumagillin analogs against osteosarcoma. European Journal Of Medicinal Chemistry, 79, 244-250.
  • Cabanillas B. J., Le Lamer A. C., Olagnier D., Castillo D., Arevalo J., Valadeau C., Coste A., Pipy B., Bourdy G, Sauvain M, Fabre N. (2014). Leishmanicidal compounds and potent PPAR gamma activators from Renealmia thyrsoidea (Ruiz & Pav.) Poepp. & Endl. Journal of Ethnopharmacology, 157, 149-155.
  • Castillo D., Sauvain M, Rivaud M., Jullian V. (2014). In vitro and In vivo activity of Benzo[c]phenanthridines against Leishmania amazonensis. Planta Medica, 80 (11), 902-906.
  • de la Cruz M. G., Malpartida S. B., Santiago H. B., Jullian V, Bourdy G. (2014). Hot and cold : medicinal plant uses in Quechua speaking communities in the high Andes (Callejon de Huaylas, Ancash, Peru). Journal of Ethnopharmacology, 155 (2), 1093-1117.
  • Deharo E, Jullian V, Bertani S., Bourdy G. (2014). La simalikalactone E, molécule antipaludique et anticancer = Simalikalactone E, anti-malarial and anticancer molecule. Biofutur, (350), 56-59.
  • Houel E., Fleury M., Jullian V, Vonthron-Senecheau C., Nardella F., Villa P., Odonne G., Eparvier V., Deharo E, Stien D. (2014). Takamalalme (Psidium acutangulum Mart ex. DC) : understanding the use of an antimalarial traditional remedy from French Guiana. Planta Medica, 80 (10), 797-797.
  • Le Lamer A.C., Authier H., Rouaud I., Coste A., Boustie J., Pipy B., Gouault N. (2014). Protolichesterinic acid derivatives: alpha-Methylene-gamma-lactones as potent dual activators of PPAR gamma and Nrf2 transcriptional factors. Bioorganic & Medicinal Chemistry Letters, 24 (16), 3819-3822.
  • Odonne G. (Coord.), Bourdy G., Ochoa Siguas N., Albán Castillo J., 2014. Plantas medicinales de los Shawi de Soledad y Atahualpa de Conchiyacu. Coédition Museo de Historia Natural de la Universidad Mayor de San Marcos (Lima, Pérou), IRD éditions (Montpellier, France), CONCYTEC (Lima, Pérou). 415 p.
  • Vansteelandt M., Roullier C., Blanchet E., Guitton Y., Pouchus Y.F., Ruiz N., Grovel O. (2014) Chapter 3: “Impact of marine-derived Penicillium species in the discovery of new potential antitumor drugs. In La Barre Stéphane; Kornprobst, Jean-Michel (Eds.), Outstanding Marine Molecules: Chemistry, Biology, Analysis, Wiley-VCH, ISBN”
  • Zebiri I., Sauvain M, Voutquenne-Nazabadioko L., Haddad M.  (2014). Phytochemical study of four plants from the family Myrsinaceae. Planta Medica, 80 (16).





  • Geiger M, Guitton Y, Vansteelandt M, Kerzaon I, Blanchet E, du Pont TR, Frisvad JC, Hess P, Pouchus YF, Grovel O. (2013). Cytotoxicity and mycotoxin production of shellfish-derived Penicillium spp., a risk for shellfish consumers. Letters In Applied Microbiology, 57 (5), 385-392.
  • Le Lamer A. C., Ibrahim N., Manjary F., Mallet-Ladeira S., Girardi C., Valentin A., Fabre N, Moulis C. (2013). Macrocyclic spermidine alkaloids from Androya decaryi L. Perrier. Molecules, 18 (4), 3962-3971.
  • Vansteelandt M, Blanchet E, Egorov M, Petit F, Toupet L, Bondon A, Monteau F, Le Bizec B, Thomas OP, Pouchus YF, Le Bot R, Grovel O. (2013). Ligerin, an Antiproliferative Chlorinated Sesquiterpenoid from a Marine-Derived Penicillium Strain. JOURNAL OF NATURAL PRODUCTS, 76 (2), 297-301.
  • Carroux A, Van Bohemen AI, Roullier C, du Pont TR, Vansteelandt M, Bondon A, Zalouk-Vergnoux A, Pouchus YF, Ruiz N. (2013). Unprecedented 17-Residue Peptaibiotics Produced by Marine-Derived Trichoderma atroviride. CHEMISTRY & BIODIVERSITY, 10 (5), 772-786.
  • Odonne Guillaume, Valadeau C., Alban-Castillo J., Stien D., Sauvain M, Bourdy G. (2013). Medical ethnobotany of the Chayahuita of the Paranapura basin (Peruvian Amazon). Journal of Ethnopharmacology, 146 (1), 127-153.
  • Rojas Durn R., Shiva Ramayoni C., Kalinowski Echegaray J., Villavicencio Gallarday C., Sauvain M. Composition of Lemon Peel essential Oil as a growth promoter in the poultry industry. WO/2013/129949.
  • Haddad M, Lelamer Anne-Cécile, Banuls L. M. Y., Vasquez P., Carraz M, Vaisberg A., Castillo D., Sauvain M, Rojas R., Kiss R. (2013). In vitro growth inhibitory effects of 13,28-epoxyoleanane triterpene saponins in cancer cells. Phytochemistry Letters, 6 (1), 128-134.
  • Hernandez P., Rojas R., Gilman R. H., Sauvain M, Lima L. M., Barreiro E. J., Gonzalez M., Cerecetto H. (2013). Hybrid furoxanyl N-acylhydrazone derivatives as hits for the development of neglected diseases drug candidates. European Journal of Medicinal Chemistry, 59, 64-74.
  • Houël E., Stien D., Bourdy G., Deharo E. (2013) Chapter 161: Quassinoids: anticancer and antimalarial activities. In Ramawat, Kishan Gopal; Merillon, Jean-Michel (Eds.), Handbook of Natural Products, Springer, ISBN 978-3-642-22143-9.”
  • Egorov M.,* Le Bot R.,* Petit F.,* Grovel O.,* Pouchus Y. F.,* Vansteelandt M.,* Preparation of fumagillol derivatives useful for the treatment or prevention of bone tumors. Brevet français (dépôt le 28/03/2011) FR 2973376 B1, 2013* : contribution équivalente des auteurs notés dans l'ordre alphabétique et selon chaque organisme (Atlanthera/Université de Nantes)





  • Girardi C., Vasquez-Ocmin P., Castillo D., Sauvain M., Rojas R., Fabre N., Haddad M. Biological activities of 13,28-epoxyoleanane triterpene saponins from two Peruvian Myrsinaceae. Revista Sociedad Quimica Peru. 78, 2012
  • Haddad M, Le Lamer A. C., Moreno y Banuls L., Carraz M, Vasquez P., Vaisberg A., Castillo D., Sauvain M, Rojas R., Kiss R. (2012). In vitro growth inhibitory effects of 13, 28-epoxyoleanane triterpene saponins in cancer cells. Planta Medica, 78 (11), 1184-1185.
  • Vansteelandt M, Kerzaon I, Blanchet E, Tankoua OF, Du Pont TR, Joubert Y, Monteau F, Le Bizec B, Frisvad JC, Pouchus YF, Grovel O. (2012). Patulin and secondary metabolite production by marine-derived Penicillium strains. FUNGAL BIOLOGY, 116 (9), 954-961.
  • Rojas R., Ruiz C., Gonzalez G., Bourdy G., Doroteo V.H., Alban J., Castillo D., Robert G., Deharo E. Role of Mitraphylline in the anti-inflammatory properties of Uncaria tomentosa bark used in Amazonian traditional medicine. J. Ethnopharmacol. 2012, 143, 801-804.
  • Rojas-Duran R., Gonzalez-Aspajo G., Ruiz-Martel C., Bourdy G, Doroteo-Ortega V. H., Alban-Castillo J., Robert G., Auberger P., Deharo E. (2012). Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark. Journal of Ethnopharmacology, 143 (3), 801-804.
  • Houël, E., Stien, D., Bourdy G., Deharo, E. (2012) Quassinoids: anticancer and antimalarial activities. In Handbook of  Natural Products. Springer Ed.
  • Le H. L., Jullian V, Bourdy G, Girardi C., Deharo E, Le Lamer A. C., Fabre N. (2012). Sensitivity enhancement in LC-ESI-MS method using mobile phase additives to quantify Simalikalactone E. Planta Medica, 78 (11), 1198-1198.
  • Rossi F., Jullian V., Pawlowiez R., Kumar-Roiné S., Haddad M., Darius HT., Gaertner-Mazouni N, Chinain M., Laurent D. (2012) Protective effect of Heliotropium foertherianum (Boraginaceae) folk remedy and its active compound, rosmarinic acid, against a Pacific ciguatoxin. Journal of Ethnopharmacology 143 : 33-40. Roué M., Quévrain E., Domart-Coulon, I., Bourguet-Kondracki M.L. (2012). Assessing calcareous sponges and their associated bacteria for the discovery of new bioactive natural products. Natural product reports., 2012, 29, 739-751
  • Ruiz S.B., Rojas Duran R., Sauvain M., Caldas J., Kalinowski J, Falcón Perez N., Shiva Ramayoni C. (2012) Evaluación del aceite essencial de Orégano (Oreganum vulgare) y extracto deshidrato de Jengibre (Zingiber officinale) como potenciales promotores de crecimiento en polos de engorde. Revista de investigaciones veterinarias del Peru – RIVEP (Lima), 23: 160-170.
  • Rivaud M., Mendoza A., Sauvain M, Valentin A., Jullian V. (2012). Short synthesis and antimalarial activity of fagaronine. Bioorganic and Medicinal Chemistry, 20 (15), 4856-4861.
  • Robert G., Jullian V, Jacquel A., Ginet C., Dufies M., Torino S., Pottier A., Peyrade F., Tartare-Deckert S., Bourdy G, Deharo E, Auberger P. (2012). Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway. Oncotarget, 3 (12), 1688-1699.
  • Fabre N., Deharo E, Le H. L., Girardi C., Valentin A., Jullian V. (2012). LC-ESI-MS/MS analysis of Quassia amara leaves tea. Is antiplasmodial activity of the tea is due to quassinoids?. Planta Medica, 78 (11), 1262-1262.
  • Bertani S., Houel E., Jullian V, Bourdy G, Valentin A., Stien D., Deharo E. (2012). New findings on Simalikalactone D, an antimalarial compound from Quassia amara L. (Simaroubaceae). Experimental Parasitology, 130 (4), 341-347.
  • El Babili F., Fouraste I., Rougaignon C., Moulis C., Chatelain C. (2012). Anatomical study of secondary tuberized roots of Harpagophytum procumbens DC and quantification of harpagoside by high-performance liquid chromatography method. Pharmacognosy Magazine, 8 (30), 175-180.
  • Bourdy G., Jullian V., Deharo E., Auberger P., Robert, G. Utilisation de la Simalikalactone E comme agent anticancéreux. Fr. Demande 2012,  FR 2970415 A1 2012 PCT Int. Appl. 2012, WO 2012095820 A1 20120719.
  • Cabanillas B. J., Le Lamer A. C., Castillo D., Arevalo J., Estevez Y., Rojas R., Valadeau C., Bourdy G, Sauvain M, Fabre N. (2012). Dihydrochalcones and benzoic acid derivatives from Piper dennisii. Planta Medica, 78 (9), 914-918.
  • Cachet N., Ho-A-Kwie F., Rivaud M., Houëll E., Deharo E, Bourdy G, Jullian V. (2012). Picrasin K, a new quassinoid from Quassia amara L. (Simaroubaceae). Phytochemistry Letters, 5 (1), 162-164.
  • Matsui M., Adib-Conquy M., Coste A., Kumar-Roine S., Pipy B., Laurent , Pauillac S. (2012). Aqueous extract of Vitex trifolia L. (Labiatae) inhibits LPS-dependent regulation of inflammatory mediators in RAW 264.7 macrophages through inhibition of Nuclear Factor kappa B translocation and expression. Journal of Ethnopharmacology, 143 (1), 24-32.
  • Mani L., Jullian V, Mourkazel B., Valentin A., Dubois J., Cresteil T., Folcher Eric, Hooper J. N. A., Erpenbeck D., Aalbersberg W., Debitus Cécile.  (2012). New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888. Chemistry and Biodiversity, 9 (8), 1436-1451.