Publications REDSTRESS

  • Bélières M, V. Sartor, P-L. Fabre, R. Poteau, G. Bordeau, N. Chouini-Lalanne, Simple electron donor molecules bases on triphenylamine and carbazole derivatives, Dyes and Pigments 2018 153:275-283.
  • Boutin JA, F. Bouillaud, E. Janda, I. Gacsalyi, G. Guillaumet, E.C. Hirsch, D.A. Kane, Nepveu, K. Reybier, P. Dupuis, M. Bertrand, M. Chhour, et al. S29434, a quinone reductase 2 reference inhibitor: main biochemical and cellular characterization. Accepted for publication in Molecular Pharmacology.
  • Cassagnes LE, Chhour M, Pério P, Sudor J, Gayon R, Ferry G, Boutin JA, Nepveu F, Reybier K.*, Oxidative stress and neurodegeneration: The possible contribution of quinone reductase 2. Free Radic Biol Med. 2018 120:56-61.
  • Mejai A, E. Najahi, G. Tchani, Perio, L. Vendier, S. Bourgeade Delmas, R. Abidi, M. Haddad, F. Nepveu and K. Reybier, Synthesis and Evaluation of Antiplasmodial Activities of Fluorinated 6-Amino2-Aryl-3H-IndoloneN –Oxides, Med Chem 2018, 8:4.
  • Villaret J, G. Marti, F. Dubois, K. Reybier, N. Gaudre, M. Haddad, A. Valentin, Adaptation of a microbead assay for the easy evaluation of traditional anti-sickling medicines: application to DREPANOSTAT® and FACA®, Pharmaceutical Biology, Pharm Biol. 2018; 56(1): 385–392.

  • Cassagnes L. E., Rakotoarivelo N., Sirigu S., Perio P, Najahi E., Chavas L. M. G., Thompson A., Gayon R., Ferry G., Boutin J. A., Valentin A., Reybier K., Nepveu F. (2017). Role of quinone reductase 2 in the antimalarial properties of indolone-type derivatives. Molecules, 22 (2).
  • Chaker A., Najahi E., Chatriant O., Valentin A., Tene N., Treilhou M., Chabchoub F., Nepveu F. (2017). New 3-substituted-2,1-benzisoxazoles: Synthesis and antimicrobial activities. Arabian Journal of Chemistry, 10 (2), S2464-S
  • Chaker A., Najahi E., Nepveu F., Chabchoub F. (2017). Microwave-assisted synthesis of chromeno[2,3-d] pyrimidinone derivatives. Arabian Journal of Chemistry, 10 (2), S3040-S
  • Chervin J., Perio P, Martins-Froment N., Pharkeovilay C., Reybier K., Nepveu F., Fabre N., Talou T., Bonzon-Ponnet V., Marti G.  (2017). Dereplication of natural products from complex extracts by regression analysis and molecular networking: case study of redox-active compounds from Viola alba subsp. dehnhardtii. Metabolomics, 13 (8).

  • Gué A.M.; Reybier K.; Sudor J. Cargou S.; Montrose A.; Microfluidic system and method for isolating and quantifying system at least one sub-population of cells from a population of cells. FR3009082 (A1); WO2015011674 (A1), US2016187336 (A1).
  • Hijona E., Aguirre L., Perez-Matute P., Villanueva-Millan M. J., Mosqueda-Solis A., Hasnaoui M., Nepveu F., Senard J. M., Bujanda L., Aldamiz-Echevarria L., Llarena M., Andrade F., Perio P, Leboulanger F., Hijona L., Arbones-Mainar J. M., Portillo M., Carpéné C. (2016). Limited beneficial effects of piceatannol supplementation on obesity complications in the obese Zucker rat: gut microbiota, metabolic, endocrine, and cardiac aspects. Journal of Physiology and Biochemistry, 72 (3), 567-582.
  • Les F., Deleruyelle S., Cassagnes L. E., Boutin J. A., Balogh B., Arbones-Mainar J. M., Biron S., Marceau P., Richard D., Nepveu F, Mauriege P., Carpene C. (2016). Piceatannol and resveratrol share inhibitory effects on hydrogen peroxide release, monoamine oxidase and lipogenic activities in adipose tissue, but differ in their antilipolytic properties. Chemico-Biological Interactions, 258, 115-125.
  • Manczak R., Fouet M., Courson R., Fabre P. L., Montrose A., Sudor J., Gue A. M., Reybier K. (2016). Improved on-chip impedimetric immuno-detection of subpopulations of cells toward single-cell resolution. Sensors and Actuators B-Chemical, 230, 825-831.
  • Rakotoarivelo N., Ibrahim N., Ibrahim H., Cabou C., Vivas L., Thompson E., Nallet J.P., Nepveu F., Valentin A. Antimalarial activity of 2-Aryl-3H-indol-3-one formulated in albumin-based nanosuspensions. Jacobs J Med. Chem. 2016, 2(1) : 006.
  • Reybier K., Ayala S., Alies B., Rodrigues J. V., Rodriguez S. B., La Penna G., Collin F., Gomes C. M., Hureau C., Faller P. (2016). Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-A Peptide and O-2. Angewandte Chemie-International Edition, 55 (3), 1085-1089.
  • Rosselin M., Tuccio B., Perio P, Villamena F. A., Fabre P. L., Durand G.  (2016). Electrochemical and spin-trapping properties of para-substituted alpha-phenyl-N-tert-butyl nitrones. Electrochimica Acta, 193, 231-239.

  • Cassagnes L. E., Perio P, Ferry G., Moulharat N., Antoine M., Gayon R., Boutin J. A., Nepveu F., Reybier K. (2015). In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones. Free Radical Biology and Medicine, 89, 126-134.
  • El Souda S S M, Ibrahim N, Perio P, Ibrahim H, Pigasse-Hénocq C, Roques C, Nepveu F. Powerful Antioxidant and Pro-Oxidant Properties of Cassia roxburghii DC. Leaves Cultivated in Egypt in Relation to Their Anti-Infectious Activities. (2015). J. Herbs, Spices Medicinal Plants. 21:410-425.
  • El Souda SS, Matloub AA, Nepveu F, Valentin A, Roques C. Phenolic composition and prospective anti-infectious properties of Atriplex lindleyi. (2015). Asian Pac. J. Trop. Dis., 5(10):930-935.
  • Ibrahim N., Ibrahim H., Sabater A. M., Mazier D., Valentin A., Nepveu F. (2015). Artemisinin nanoformulation suitable for intravenous injection: preparation, characterization and antimalarial activities. International Journal of Pharmaceutics, 495 (2), 671-679.
  • Lee CS, Aroua MK, Daud WMAW, Cognet P, Peres-Lucchese Y, Fabre PL, Reynes O, Latapie L. (2015). A review: Conversion of bioglycerol into 1,3-propanediol via biological and chemical method. Renewable & Sustainable Energy Reviews, 42, 963-972.

  • Abdoulkadri A.M., Boubier G., Fabre PL, Electrochemical determination of iron(II) at a Nafion-1,10-phenanthroline-modified carbon paste electrode: Assessing the correlation between preconcentration potential, surface morphology and impedance measurements. (2014). ChemXPress 6:71-90.
  • Chaker A., Zribi F., Nepveu F., Chabchoub F. (2014). Microwave irradiation: Novel and facile methods for the synthesis of new pyrimidinones. Chinese Chemical Letters, 25 (8), 1207-1210.
  • Ibrahim N., Ibrahim H., Dormoi J., Briolant S., Pradines B., Moreno A., Mazier D., Legrand P., Nepveu F. (2014). Albumin-bound nanoparticles of practically water-insoluble antimalarial lead greatly enhance its efficacy. International Journal of Pharmaceutics, 464 (1-2), 214-224.
  • Najahi E., Rakotoarivelo N. V., Valentin A., Nepveu F. (2014). Amino derivatives of indolone-N-oxide: Preparation and antiplasmodial properties. European Journal of Medicinal Chemistry, 76, 369-375.
  • Najahi E., Valentin A., Fabre P. L., Reybier K., Nepveu F. (2014). 2-Aryl-3H-indol-3-ones: Synthesis, electrochemical behaviour and antiplasmodial activities. European Journal of Medicinal Chemistry, 78, 269-274.
  • Nepveu F., Najahi E., Valentin A. (2014). Antimalarial Activities of Indolones and Derivatives. Current Topics in Medicinal Chemistry, 14 (14), 1643-1652.
  • Rakotoarivelo N V, Najahi E, Perio P, Hollande E, Nepveu F, Isoindolinotriazole derivatives: synthesis by the azide alkyne cycloaddition click chemistry. (2014). Journal of Advances in Chemistry, 10(7):2937-2943.
  • Rakotoarivelo N. V., Perio P, Najahi E., Nepveu F. (2014). Interaction between antimalarial 2-Aryl-3H-indol-3-one derivatives and human serum albumin. Journal of Physical Chemistry B, 118 (47), 13477-13485.
  • Ribaut C., Bordeau G., Perio P, Reybier K., Sartor V., Reynes O., Fabre P. L., Chouini-Lalanne N. (2014). EPR spectroelectrochemical investigation of guanine radical formation and environment effects. Journal of Physical Chemistry B, 118 (9), 2360-2365.
  • Thi Thu Vu, M. Fouet, A-M. Gue, J. Sudor, A new and easy surface functionalization technology for monitoring wettability in heterogeneous nano- and microfluidic devices, Sensors and Actuators B: Chemical, 2014, 196, 64-70.
  • Vu T. T., Fouet M., Gue A. M., Sudor J.  (2014). A new and easy surface functionalization technnology for monitoring wettability in heterogeneous nano- and microfluidic devices. Sensors and Actuators B-Chemical, 196, 64-70.

  • Cassagnes L. E., Herve V., Nepveu F., Hureau C., Faller P., Collin F. (2013). The Catalytically Active Copper-Amyloid-Beta State: Coordination Site Responsible for Reactive Oxygen Species Production. Angewandte Chemie-International Edition, 52 (42), 11110-11113.
  • Chaker A., Najahi E., Chatriant O., Valentin A., Téné N., Treilhou M., Chabchoub F., Nepveu F. New 3-substituted-2,1-benzisoxazoles: Synthesis and antimicrobial activities,ÂArab.J. Chem., 2013
  • Chaker A., Najahi E., Nepveu F., Chabchoub F. Microwave-assisted synthesis of chromeno[2,3-d]pyrimidinone derivatives, Arab.J. Chem., 2013
  • Ibrahim H, Ibrahim N, Nepveu F. n° 13/54605, déposé le 22 mai 2013 ; « Utilisation de nanoparticules pour la préparation de compositions antipaludéennes solubles dans l'eau et injectables».
  • Ibrahim H., Couderc F., Perio P, Collin F., Nepveu F. (2013). Behavior of N-oxide derivatives in atmospheric pressure ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 27 (5), 621-628.
  • Montrose A., Cargou S., Nepveu F., Manczak R., Gue A. M., Reybier K. (2013). Impedimetric immunosensor for the detection of circulating pro-inflammatory monocytes as infection markers. Biosensors & Bioelectronics, 49, 305-311.
  • Najahi E., Valentin A., Tene N., Treilhou M., Nepveu F. (2013). Synthesis and biological evaluation of new bis-indolone-N-oxides. Bioorganic Chemistry, 48, 16-21.
  • Najahi E., Vanthuyne N., Nepveu F., Jean M., Alkorta I., Elguero J., Roussel C. (2013). Atropisomerization in N-aryl-2(1H)-pyrimidin-(thi)ones: A Ring-Opening/Rotation/Ring-Closure Process in Place of a Classical Rotation around the Pivot Bond. Journal of Organic Chemistry, 78 (24), 12577-12584.
  • Nepveu F., Turrini F. (2013). Targeting the redox metabolism of Plasmodium falciparum. Future Medicinal Chemistry, 5 (16), 1993-2006.
  • Nguyen H. Y. T., Vo B. H. T., Nguyen L. T. H., Bernad J., Alaeddine M., Coste A., Reybier K., Pipy B., Nepveu F. (2013). Extracts of Crinum latifolium inhibit the cell viability of mouse lymph oma cell line EL4 and Induce activation of anti-tumour activity of macrophages in vitro. Journal of Ethnopharmacology, 149 (1), 75-83.
  • Partyka J., Foret F., Vu T. T., Sudor J. (2013). Polydopamine coated capillaries for ce separations. Chemicke Listy, 107 (3), S412-S
  • Yen N. T. H., Ibrahim H., Reybier K., Perio P, Souard F., Najahi E., Fabre P. L., Nepveu F.  (2013). Pro-oxidant properties of indolone-N-oxides in relation to their antimalarial properties. Journal of Inorganic Biochemistry, 126, 7-16.

  • Erpenbeck D., Hooper J.N.A., Bonnard I., Sutcliffe P., Chandra M., Perio P., Wolff C., Banaigs B., WÃrheide G., Debitus C., Petek S. (2012). Evolution, radiation and chemotaxonomy of Lamellodysidea, a demosponge genus with anti-plasmodial metabolites, Marine Biology. 159:1119-1127
  • Pantaleo A., Ferru E., Vono R., Giribaldi G., Lobina O., Nepveu F., Ibrahim H., Nallet J. P., Carta F., Mannu F., Pippia P., Campanella E., Low P. S., Turrini F. (2012). New antimalarial indolone-N-oxides, generating radical species, destabilize the host cell membrane at early stages of Plasmodium falciparum growth: role of band 3 tyrosine phosphorylation. Free Radical Biology and Medicine, 52 (2), 527-536.
  • Reybier K., Thi H. Y. N., Ibrahim H., Perio P, Montrose A., Fabre P. L., Nepveu F. (2012). Electrochemical behavior of indolone-N-oxides: relationship to structure and antiplasmodial activity. Bioelectrochemistry, 88, 57-64.
  • Ibrahim H., Furiga A., Najahi E., Henocq C. P., Nallet J. P., Roques C., Aubouy A, Sauvain M, Constant P., Daffe M., Nepveu F. (2012). Antibacterial, antifungal and antileishmanial activities of indolone-N-oxide derivatives. Journal of Antibiotics, 65 (10), 499-504.
  • Motta JP, Bermudez-Humaran LG, Deraison C, Martin L, Rolland C, Rousset P, Boue J, Dietrich G, Chapman K, Kharrat P, Vinel JP, Alric L, Mas E, Sallenave JM, Langella P, Vergnolle N.  (2012). Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis. SCIENCE TRANSLATIONAL MEDICINE, 4 (158), 158ra144.





Jeudi 8 octobre 2020 : Séminaire

25 septembre 2020 |  

Le prochain séminaire se tiendra le jeudi 8 octobre à 14h30 en présentiel et en visio. Nous aurons le plaisir d'écouter,...

Vendredi 25 septembre 2020 : Séminaire

17 septembre 2020 |  

Reprise des séminaires de l'UMR vendredi 25 septembre à 14h ! François Chassagne, nouvelle recrue de l'unité en tant que CR...

septembre 2020 : Recrutement

11 septembre 2020 |  

Bienvenue à Alice Gadea, nouvelle MCU au sein du service de Pharmacognosie-botanique-mycologie de la faculté de pharmacie de Toulouse, et qui...

Mercredi 8 juillet 2020 : Workshop sur les réseaux moléculaires

29 juin 2020 |  

Il s'agit de la 2ème partie, pratique cette fois, du séminaire de Sergio Ortiz (post-doc équipe PEPS) sur les réseaux moléculaires....

Jeudi 25 juin 2020 : Séminaire

23 juin 2020 |  

Le prochain séminaire aura lieu jeudi 25 juin à 14h30 en visioconférence. Romina Pacheco, doctorante de l'équipe PEPS, nous présentera une...

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